Hairy cell leukemia exhibits immunologic and functional features typical of which cells?

Hairy cell leukemia is characterized by the proliferation of atypical B lymphocytes that have distinctive morphology and immunophenotypic markers. These cells exhibit surface markers typical of B cells, such as CD19, CD20, and CD22, along with the expression of the specific marker CD11c and CD25. This profile confirms that hairy cell leukemia derives from B lymphocytes and reflects their functional properties, including involvement in humoral immunity.

Additionally, while monocytes may not be the primary focus of hairy cell leukemia, their functional features as part of the immune response complement the atypical B lymphocytes. A comprehensive understanding of hairy cell leukemia recognizes the interplay between B lymphocytes and monocytes, especially in the context of immune dysregulation often seen in this type of leukemia.

The other choices include cell types that do not align with the primary features of hairy cell leukemia. T lymphocytes and granulocytes are more representative of different hematologic malignancies and do not exhibit the same immunologic characteristics as hairy cells. Plasma cells and NK cells, while also part of the immune system, do not share the specific functional traits or immunologic markers that define hairy cell leukemia. Dendritic cells and neutrophils belong to different lineages and serve distinct