In a quantitative B lymphocyte assay, what is the expected percentage of B lymphocytes among total lymphocytes?

In a typical quantitative assessment of B lymphocytes among total lymphocytes, the expected percentage generally falls in the range of 10% to 20%. This is due to the fact that B cells usually comprise a smaller portion of the total lymphocyte population compared to T cells. While the exact percentage can vary depending on the individual and specific conditions, a value close to 20% is considered within the normal range for healthy adults.

In this scenario, the choice of 20% accurately reflects the typical distribution seen in peripheral blood, reinforcing the understanding that while B lymphocytes are essential for humoral immunity and the production of antibodies, they do not dominate the lymphocyte population compared to T lymphocytes.