What is the outcome of C3b after being cleaved by C3 inactivator?

After being cleaved by C3 inactivator, C3b is converted to C3c and C3d, which are breakdown products of the complement component C3. This process reflects the regulation of complement activation, which is essential for controlling inflammation and preventing damage to host tissues.

C3b plays a crucial role in opsonization, where it tags pathogens for destruction by immune cells. However, when the complement system is overactive, C3b must be regulated to avoid excessive inflammation and tissue injury. The cleavage of C3b into C3c and C3d is a key part of this regulation, leading to the eventual clearance of these components from circulation.

Understanding the conversion of C3b into C3c and C3d highlights the importance of complement component regulation in maintaining immune homeostasis and preventing pathological conditions associated with uncontrolled complement activation.