What is the typical profile for chronic active hepatitis due to hepatitis B virus?

The typical profile for chronic active hepatitis due to hepatitis B virus indeed includes the presence of HBsAg (Hepatitis B surface antigen) and IgM anti-HBc (Immunoglobulin M antibody to Hepatitis B core antigen) being positive. The presence of HBsAg indicates an ongoing infection with the Hepatitis B virus, which is a hallmark of chronic hepatitis.

Additionally, while IgM anti-HBc is typically associated with acute infection, its presence during chronic active hepatitis suggests that the patient may be experiencing an exacerbation or flare of the chronic disease. Therefore, in this scenario, having both HBsAg and IgM anti-HBc positive demonstrates an actively replicating virus and reinforces the diagnosis of chronic active hepatitis.

The other options do not reflect the typical profile for chronic active hepatitis due to hepatitis B. For instance, HBsAg negative, anti-HBs positive would suggest either recovery from a past infection or vaccination, which does not align with chronic active disease. Similarly, the presence of IgM anti-HBc without HBsAg would also be inconsistent with the chronic active form, indicating either early acute or resolved infection. Therefore, the scenario described by option C accurately represents the chronic active hepatitis profile due to Hepatitis